Table 5.

Odds Ratio of Mean Relative Abundances or Presence/Absence of Bacterial Taxa Associated With One Increase in Packs Smoked

Taxonomy	Odds ratioa (95% CI)	p value
Abundance association testb
Class Erysipelotrichi	1.88 (1.22, 2.89)	.004
Order Erysipelotrichales	1.88 (1.22, 2.89)	.004
Family Erysipelotrichaceae	1.88 (1.22, 2.89)	.004
Family Peptostreptococcaceae	1.67 (1.02, 2.69)	.04
Genus Slackia	2.75 (1.57, 4.76)	.0004
Genus Catenibacterium	1.90 (1.17, 3.03)	.01
Genus Collinsella	1.73 (1.05, 2.89)	.03
Presence/absence association testc
Genus Slackia	28.5 (3.9, 208.51)	.001
Genus Mitsuokella	20.7 (1.03, 411.58)	.048

CI = confidence interval.

^aOdds ratio of the mean relative abundance of taxa (abundance association test) or the mean presence probability of taxa (presence/absence association test) comparing smokers to never-smokers adjusting for age, sex, body mass index, education, and betel quid use.

^bBeta regression with logit transformation based on the continuous variable of relative abundance of taxa, replacing zeros with 10⁻⁶.

^cLogistic regression based on the dichotomous variable for presence/absence of taxa with a prevalence of greater than 10% and less than 90%.