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. 2020 Jul 16;49:107263. doi: 10.1016/j.carpath.2020.107263

Table 2.

Histologic features of lung tissue in 14 autopsy cases of COVID-19.

Case Number 1 2 3 4 5 6 7 8 9 10 11 12 13 14 N=14*
Symptom onset – death (days) 6 7 10 12 16 17 19 21 21 23 28 30 30 50 20.7
Total no. of slides 20 20 28 16 23 21 12 16 15 23 17 26 20 25 20.1
No. of slides from the lung 11 11 13 8 11 11 6 7 8 9 10 15 5 8 9.5
Pulmonary capillary congestion +++ +++ +++ +++ ++ ++ +++ +++ +++ +++ ++ +++ ++ ++ 100.0
DAD, acute + + ++ + + + + + + + ++ - + - 85.7
Pulmonary edema + +++ + + + + + + + ++ + + + ++ 100.0
DAD, organizing - ++ ++ ++ +++ +++ ++ +++ ++ ++ +++ +++ ++ + 92.9
Pneumocyte hyperplasia - + ++ + +++ ++ ++ +++ ++ + +++ ++ ++ + 92.9
Multinucleated cells - - + + +++ ++ ++ ++ + + ++ ++ + + 85.7
Squamous metaplasia - + ++ ++ + + + + + + +++ ++ + - 85.7
Acute bronchopneumonia +++ +++ - +++ +++ ++ - + ++ ++ ++ ++ + - 78.6
Pulmonary hemorrhage +++ ++ + + +++ ++ + + + + + +++ + ++ 100.0
Infarct - - - - + - - - - - + - - - 14.3
Pulmonary microthrombi - + + - + + - + + + + + + + 78.6
Thrombi in mid-sized pulmonary arteries - + - - + + - - - - + - - + 35.7
Special stains + + - + - + - - - + + + - - 50.0

+, mild; ++, moderate; +++, marked; - not present. *Categorical variables are expressed as percentages, numerical variables are expressed as means.