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. 2020 Jul 9;14:732. doi: 10.3389/fnins.2020.00732

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Copyright © 2020 Balseanu, Grigore, Pinosanu, Slevin, Hermann, Glavan and Popa-Wagner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrical stimulation led to increased neurogenesis in the subventricular zone. Analysis of the numbers of co-localized BrdU/DCX cells in the subventricular zone revealed a significant increase (18-fold in the number of BrdU/DCX+ cells in the ipsilateral hemisphere of ES animals) (A, and inset) as compared with the contralateral hemisphere of the same animals (B, and inset; E). In control animals, despite of large numbers of DCX and BrdU-positive cells, we could not detect clear co-localized BrdU/DCX cells both in the ipsilateral and contralateral hemisphere (C vs. D). ***P = 0.0001 by one-way ANOVA followed by Dunnett’s multiple comparisons test.