Table 3.

Association of RPS27L Gene Expression with FEV₁/FVC Ratio

Variables	Model 1		Model 2		Model 3*
	β-Value (95% CI)	P Value	β-Value (95% CI)	P Value	β-Value (95% CI)	P Value
Gene expression	12.56 (5.41 to 19.71)	0.001	11.38 (4.40 to 18.36)	0.002	14.07 (5.59 to 22.55)	0.001
Obese asthma	—	—	−4.10 (−7.07 to −1.12)	0.007	−3.72 (−6.95 to −0.48)	0.03
Genotype (T/C)†	—	—	—	—	0.67(−3.81 to 5.14)	0.77
Genotype (C/C)†	—	—	—	—	−10.04(−18.95 to −1.13)	0.03

Definition of abbreviations: CI = confidence interval; RPS27L = 40S ribosomal protein S27-like.

^*Both gene expression and genetic variant were associated with percentage FEV₁/FVC ratio.

^†Major allele homozygous (T/T) was the reference group.