Table 4.
Association of RPS27L Gene Expression with Percent Predicted ERV
Variables | Model 1 |
Model 2 |
Model 3* |
|||
---|---|---|---|---|---|---|
β-Value (95% CI) | P Value | β-Value (95% CI) | P Value | β-Value (95% CI) | P Value | |
Gene expression | 35.88 (11.76 to 60.00) | 0.004 | 30.62 (7.74 to 53.49) | 0.009 | 30.00 (1.49 to 58.51) | 0.04 |
Obese asthma | — | — | −18.25 (−28.00 to −8.50) | 0.007 | −18.37 (−29.26 to −7.49) | 0.03 |
Genotype (T/C)† | — | — | — | — | −3.40 (−18.46 to 11.66) | 0.65 |
Genotype (C/C)† | — | — | — | — | −11.95 (−41.91 to 18.01) | 0.43 |
Definition of abbreviations: CI = confidence interval; ERV = expiratory reserve volume; RPS27L = 40S ribosomal protein S27-like.
Gene expression, but not the genetic variant, was associated with ERV percent predicted.
Major allele homozygous (T/T) was the reference group.