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. 2020 Jul 15;202(2):219–229. doi: 10.1164/rccm.202003-0541OC

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Copyright © 2020 by the American Thoracic Society

This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/). For commercial usage and reprints, please contact Diane Gern (dgern@thoracic.org).

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Figure 4. — Assessment of the small airway epithelia of healthy nonsmokers (n = 20; white circles) and smokers (n = 23; gray circles) for expression of genes that may be relevant to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. See text for details regarding the possible relevance of these genes to small airway epithelia infection by SARS-CoV-2. Quantification was by RNA sequencing (Illumina HiSeq 2500). A one-way ANOVA was used for analysis. (A) ADAM10. (B) ADAM17. (C) TMPRSS2. (D) TMPRSS11A. (E) TMPRSS11D. (F) FURIN. (G) CTSL. (H) PI4KB. **P < 0.01. FPKM = fragments per kilobase of exon per million fragments sequenced; NS = nonsignificant.