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. 2020 Jul 6;14(7):e0008413. doi: 10.1371/journal.pntd.0008413

Fig 5. YS-derived microglia progenitors in the E11.5 embryos brain.

Fig 5

(A) Representative images of E11.5 embryo with the outside YS and placenta from mock-infected and ZIKV-infected dam on E6.5. (B and C) Representative confocal images of embryonic brains from mock and ZIKV-infected dams. Microglial progenitors (F4/80, red) co-stained with antibodies against ZIKV E proteins (green) (arrow). (D) Quantitative analysis of the numbers of F4/80+ cells per area (n = 5 in mock from 5 dams, n = 5 in ZIKV from 5 dams), and the percentage of ZIKV infected F4/80+ cells in the embryonic brain from mock-infected and ZIKV-infected dam (n = 5 in mock from 5 dams, n = 5 in ZIKV from 3 dams). Unpaired t test, ** P <0.01 and **** P <0.0001.