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. 2020 Jul-Sep;24(3):283–288. doi: 10.5935/1518-0557.20200003

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Representative immunofluorescence images of mouse oocytes stained for spindle and chromosomes

A & B) MII oocyte, exposed to FF of oocyte donor, with normal spindle morphology and chromosomes correctly positioned in the equator.

C & D) MII oocyte, exposed to FF of patient with endometriosis, showing abnormal spindle morphology (red arrow) and chromosomes localized apart from the spindle (yellow arrow).

A & C) Composed image of transmitted light + spindle & chromosomal staining.

B & D) Composed image of spindle & chromosomal staining.