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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Nat Prod Rep. 2020 Feb 18;37(5):717–736. doi: 10.1039/c9np00066f

Figure 11. PERK pathway activators with differential selectivity.

Figure 11.

Cephalostatin-ritterazine hybrid was shown to have selectivity for the PERK branch, while withaferin A is non-selective. For ritterostatin GN1N, red and blue colors indicate cephalostatin 1 and ritterazine B fragments, respectively. Probe position and label are indicated in green.