Skip to main content
. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Nat Prod Rep. 2020 Feb 18;37(5):717–736. doi: 10.1039/c9np00066f

Figure 13. Structures of GH47 family α-mannosidase inhibitors as ERAD inhibitors.

Figure 13.

Kifunensine is 100-fold more potent than 1-deoxymannojirimycin. Structural differences are indicated in red. Hydroxy groups that coordinate the essential Ca2+ in the active site are indicated in blue.