Fig. 6.

DEX inhibits esophageal cancer tumor growth in vivo. KYSE150 cells treated with negative control or DEX were subcutaneously injected into the murine. (a) Tumor volume was recorded once a week. (b) Murine xenograft tumor was weighed following four-week inoculation. (c) The expression of miR-143-3p and EPS8 was analyzed in resected tumor tissues by qRT-PCR. (d) The protein level of EPS8 was determined in resected tumor tissues by Western blot. *P < 0.05. DEX, dexmedetomidine; EPS8, epidermal growth factor receptor pathway substrate 8; qRT-PCR, quantitative real time PCR.