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. Author manuscript; available in PMC: 2021 Mar 26.
Published in final edited form as: J Med Chem. 2020 Mar 10;63(6):2854–2876. doi: 10.1021/acs.jmedchem.9b01189

Figure 7.

Figure 7.

Cellular thermal shift assay results for A91 and 4u. (A) Thermal melting profile of PPARα. (B) Dose-dependent stabilization of PPARα by A91 and 4u. Experiment was run at 45.5 °C, the Tagg(75).