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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Hepatology. 2020 Jun 29;72(4):1191–1203. doi: 10.1002/hep.31115

Figure 1. Indole is relevant to human obesity and increased liver fat content.

Figure 1.

The relevance of indole to human pathophysiology. (A) Body mass index (BMI). (B) Serum levels of indole and its correlation with BMI. (C) HOMA-IR was calculated using serum levels of insulin and glucose. (D) Hepatic fat content was estimated from liver attenuation (HU) based on CT-scan images. Left three panels, representative images; bar graph, quantitative data. A smaller HU indicates greater hepatic fat content. For A - D, the study included 75 lean, 51 overweight, and 11 obese subjects. Numeric are means ± SEM. *, P < 0.05 and **, P < 0.01 Obese vs Lean.