Figure 3.

Final Estimated Causal Model. Physical function, electroencephalogram alpha power, and lowest temperature during CPB have effects on delirium mediated through their impact on burst-suppression during CPB. None of these predictors were found to have a separate direct effect on delirium outside of indirect effects through burst-suppression during CPB. Age had a direct positive effect on delirium. This model also suggests that the significant univariate association of age with burst-suppression during CPB (see results) may partly be mediated through one or more of the exogenous predictors on the left.

EEG, electroencephalogram; CPB, cardiopulmonary bypass