Table 1.
; Percent relative inhibition and half-maximal inhibition concentration (IC50) on HIV-1 PR and RT activities of LR crude extracts, pepstatin, NVP and DMSO.
| Tested compounds | HIV-1 PR |
HIV-1 RT |
||
|---|---|---|---|---|
| % Inhibition | IC50 | % Inhibition | IC50 | |
| LRH (1 mg/ml) | 88.97 ± 1.57∗ | 0.53 ± 0.02 mg/mL | 9.94 ± 3.12 | ND |
| LRE (1 mg/ml) | 37.43 ± 1.08∗ | ND | 53.03 ± 3.32∗ | ND |
| LRW (1 mg/ml) | 25.72 ± 3.41∗ | ND | 55.56 ± 3.51∗ | ND |
| Pepstatin (1 mM) | 81.48 ± 0.76∗ | 0.32 ± 0.05 mM | ND | ND |
| NVP (200 μM) | ND | ND | 99.02 ± 0.98∗ | 0.16 ± 0.00 μM |
| DMSO (1%, v/v) | 8.07 ± 0.13 | ND | 2.34 ± 0.59 | ND |
*P < 0.05 versus the vehicle control. ND, Not determine.