FIGURE 2.

Cost-effectiveness acceptability curve of the probabilistic (2-D) cost-effectiveness analysis of early anti-TNF-α intervention vs standard care from a public health care payer perspective. The curves, reflective of uncertainty in the ICER, represent the proportion of microsimulations wherein each strategy is cost-effective over a range of willingness-to-pay (in Canadian dollars) thresholds. Although a willingness-to-pay threshold for a week in steroid-free remission is unknown in Canada, at a theoretical willingness-to-pay threshold of CAD$2500 per week in steroid-free remission, neither strategy is dominant.