TABLE 3.

The Health Status at 6, 12, 18, 24, 30, and 36 Months Postdiagnosis in the Matched RISK-PROKIIDS Comparator Groups

Health Status	Standard Care	Early Intervention With Biologics	P
	n = 237	n = 123
No. subjects in steroid-free remission at 6 mo (%)	93 (39.2)	65 (52.8)	0.019*
No. subjects in steroid-free remission at 12 mo (%)	125 (52.7)	75 (61.0)	0.168
No. subjects in steroid-free remission at 18 mo (%)	132 (55.7)	82 (66.7)	0.058
No. subjects in steroid-free remission at 24 mo (%)	154 (65.0)	92 (74.8)	0.075
No. subjects in steroid-free remission at 30 mo (%)	167 (70.5)	87 (70.7)	1
No. subjects in steroid-free remission at 36 mo (%)	177 (74.7)	88 (71.5)	0.607
No. steroid-free remission semesters in 36 mo per group, mean (SD)	3.59 (1.61)	3.98 (1.86)	0.036*
Maximum consecutive steroid-free remission semesters in 36 mo per group, mean (SD)	3.02 (1.66)	3.61 (1.97)	0.003*
Total days in hospital at 36 mo per group, mean (SD)	3.76 (10.51)	3.97 (13.37)	0.872
No. subjects hospitalized (%)	84 (35.4)	45 (36.6)	0.922

Health state at diagnosis was based on the weighted Pediatric Crohn’s Disease Activity Index and the steroid state of the patients.

*P < 0.05.