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The safety concentration of TR in HaCaT cells is 100 μM. (A) The IC50 value of HaCaT cells treated by TR for 24 h, determined by CCK8 assay. (B) The cell viability of HaCaT cells treated by TR in the indicated concentration for 24 h, performed by CCK8 assay. Data represent the mean ± SD (n = 3). P-value was calculated by two-tailed Student’s t-test. ***P < 0.001, NS, not significant.
