Table 1.

Several missense mutations have been identified in the entire genome of nCOVID-19 strains (Phan, 2020a).

Location	Number of mutations	Codon	Mutation	Region(s) of strain(s)
Matrix protein	2		1
		209	Asp → His	Singapore
3′UTR	3		N/A
Intergenic region	5		N/A
Intergenic region	6		N/A
Nucleocapsid protein	7		4
		148	Thr → Ile	China (Shenzhen)
		194	Ile → Leu	China (Shenzhen) China (Foshan) USA USA
		202	Ser → Asn	Australia
		344	Pro → Ser	Hong Kong (Guangzhou)
5′ UTR	8		N/A
Spike polyprotein	14		8
		32	Phe → Ile	China (Wuhan)
		49	His → Tyr	China (Guangdong)
		247	Ser → Arg	Australia
		354	Asn → Asp	China (Shenzhen)
		364	Asp → Tyr	China (Shenzhen)
		367	Val → Phe	France
		614	Asp → Gly	Germany
		1143	Pro → Leu	Australia
ORF1ab polyprotein	48		29
		117	Ala → Thr	USA
		309	Pro → Ser	France
		428	Ser → Asn	USA
		609	Thr → Ile	USA
		1176	Ala → Val	Japan
		1599	Leu → Phe	Korea
		1607	Ile → Val	USA
		2194	Met → Thr	China (Shenzhen)
		2235	Leu → Ile	China (Wuhan)
		2244	Ile → Thr	China (Wuhan)
		2251	Gly → Ser	China (Wuhan)
		2345	Ala → Val	China (Shandong)
		2534	Gly → Val	China (Wuhan)
		2579	Asp → Ala	China (Wuhan)
		2708	Asn → Ser	China (Wuhan)
		2908	Phe → Ile	China (Wuhan)
		3058	Thr → Ile	France
		3099	Ser → Leu	China (Shenzhen)
		3606	Leu → Phe	China (Yunnan) China (Shandong) China (Chongqing) Singapore France USA
		3764	Glu → Asp	Japan
		3833	Asn → Lys	China (Wuhan)
		5308	Trp → Cys	Taiwan
		5579	Thr → Ile	USA
		6075	Ile → Thr	England
		6083	Pro → Leu	Japan
		6309	Phe → Tyr	China (Sichuan)
		6565	Glu → Asp	China (Shenzhen)
		6958	Lys → Arg	China (Wuhan)
		7018	Asp → Asn	China (Wuhan)