Fig. 1.

Temporal evolution of immune cells populations in our two MS patients who developed COVID-19 under alemtuzumab treatment across disease stages. A) Case 1: prior to infection, during COVID-19 and the next 2 months. B) Case 2: prior to alemtuzumab infusion, prior to infection, during COVID-19, and the next 2 months. Total count of lymphocytes (normal values: 1000–4000 cells/µL), neutrophils (normal values:1800–7500 cells/µL) and monocytes (normal values: 130–900 cells/µL) are represented in lines. Lymphocyte profile (CD4, CD8, CD19 and NK cells) are showed in bars, when available. Y2=year 2, 1M=1 month, 2M=2 months.