Table 3.
Respiratory data and Follow up data of the two groups. Numbers denotes row numbers (percentages) or median [interquartile range]. SpO2 = peripheral capillary oxygen saturation; FiO2 = Fractional concentration of oxygen in inspired air; CPAP = Continuous Positive Airway Pressure; Peep = positive end expiratory pressure.
| Controls (n=68) | Tocilizumab (n=90) | |
|---|---|---|
| Respiratory support needed at hospital admision | ||
| 1) No respiratory support | 20 (29.4%) | 18 (20%) |
| SpO2 (%) | 95 [88–98] | 93 [88–97] |
| 2) Low flow cannula | 13 (19.1%) | 8 (8.8%) |
| SpO2 (%) | 95 [92–97] | 94 [92–98] |
| FiO2 (%) | 28 [24–31] | 31 [24–31] |
| 3) High flow mask | 24 (35.3%) | 42 (46.6%) |
| SpO2 (%) | 95 [91–98] | 94 [88–100] |
| FiO2 (%) | 60 [35–100] | 60 [40-100] |
| 4) CPAP | 11 (16.2%) | 22 (24.4%) |
| SpO2 (%) | 94 [88–98] | 95 [89–99] |
| FiO2 (%) | 50 [40-60] | 55 [40–100] |
| Peep (cm H2O) | 13 [10–12.5] | 13 [10–20] |
| Longitudinal follow up | ||
| Patients needing mechanical ventilation | 6 (8.82%) | 13 (14.4%) |
| Respiratory System Infections | 4 (5.9%) | 6 (6.6%) |
| Etiological agent for respiratory system infections | Streptococcus Epidermidis (n=1) Clamydia Pneumoniae (n=1) Mycoplasma Pneumoniae (n=1) Staphilococcus Hominis (n=1) |
Mycoplasma Pneumoniae (n=2) Clamidya Pneumoniae (n=2) Staphilococcus Hominis (n=1) Cytomegalovirus (n=1) |
| Pulmunary Embolism | Not known | 12 (13.3%) |
| Total deaths | 34 (50%) | 7 (7.7%) |