Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Simplified Diagnostic Criteria for AIH
| Variable | Cutoff | Point |
|---|---|---|
| Autoantibodies | ANA or SMA 1:40 | 1 |
| ANA or SMA ≥1:80 | 2 | |
| LKM (≥1:40) or SLA positive | 2 | |
| IgG | >ULN | 1 |
| >1.1×ULN | 2 | |
| Liver histology | Compatible | 1 |
| Typical | 2 | |
| Absence of viral hepatitis | Yes | 2 |
≥6, Probable autoimmune hepatitis (AIH); ≥7, definite AIH.
ANA, anti-nuclear antibodies; SMA, anti-smooth muscle antibodies; LKM, liver kidney/microsome; SLA, soluble liver antigen; IgG, immunoglobulin G; ULN, upper limit of normal.
