Fig. 3.

Receiver operating characteristic curve and corresponding AUC of sPGII for the diagnosis of gastric cancer (GC). The AUC for sPGII did not show significant sensitivity and specificity for total GC (A) and DGC (B). However, when the patients with early DGC were grouped with age 40 years as the cutoff, sPGII showed significantly higher diagnostic power for patients with early-stage DGC under 40 years of age (AUC 0.766, 75.0% sensitivity, 74.2% specificity) (D) than those 40 years or older (C).

AUC, area under the curve; sPG, serum pepsinogen; DGC, diffuse gastric cancer.