Table 3.
Diagnostic Performance of FIB-4 and NFS Indicating Low and High Risk for Advanced Fibrosis in Our Sample (n=463)
| Cutoff | Sensitivity (%) | Specificity (%) | FN | FP | PPV | NPV | PLR | NLR |
|---|---|---|---|---|---|---|---|---|
| FIB-4 | ||||||||
| <1.3 | 64 | 74 | 0.358 | 0.262 | 0.342 | 0.907 | 2.452 | 0.485 |
| >2.67 | 15 | 97 | 0.852 | 0.029 | 0.522 | 0.843 | 5.145 | 0.877 |
| NFS | ||||||||
| <–1.455 | 71 | 63 | 0.284 | 0.369 | 0.291 | 0.913 | 1.940 | 0.450 |
| >0.676 | 15 | 96 | 0.852 | 0.037 | 0.462 | 0.842 | 4.042 | 0.884 |
FIB-4, fibrosis-4 index; NAFLD, nonalcoholic fatty liver disease; NFS, NAFLD fibrosis score; FN, false negative; FP, false positive; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.