Table 2.
Correlation between Tumor Cellularity and the Clinicopathological Characteristics of Pancreatic Ductal Adenocarcinoma
| Characteristics | Tumor cellularity <30% (n=107) | Tumor cellularity ≥30% (n=68) | p-value |
|---|---|---|---|
| Age, yr | 0.656 | ||
| <65 | 42 (59.1) | 29 (40.9) | |
| ≥65 | 65 (62.5) | 39 (37.5) | |
| Sex | 0.257 | ||
| Male | 60 (57.7) | 44 (42.3) | |
| Female | 47 (66.2) | 24 (33.8) | |
| Tumor location | 0.055 | ||
| Head | 67 (56.3) | 52 (43.7) | |
| Body/tail/others | 40 (71.4) | 16 (28.6) | |
| Median tumor size, cm | 0.371 | ||
| <3 | 43 (57.3) | 32 (42.7) | |
| ≥3 | 64 (64.0) | 36 (36.0) | |
| Lymph node involvement | 0.687 | ||
| Absent | 41 (63.1) | 24 (36.9) | |
| Present | 66 (60.0) | 44 (40.0) | |
| Histology (differentiation) | <0.001 | ||
| Well | 16 (88.9) | 2 (11.1) | |
| Moderate | 86 (62.3) | 52 (37.7) | |
| Poor | 5 (26.3) | 14 (73.7) | |
| Angiolymphatic invasion | 0.227 | ||
| Absent | 42 (56.0) | 33 (44.0) | |
| Present | 65 (65.0) | 35 (35.0) | |
| Venous invasion | 0.735 | ||
| Absent | 57 (60.0) | 38 (40.0) | |
| Present | 50 (62.5) | 30 (37.5) | |
| Perineural invasion | 0.497 | ||
| Absent | 12 (54.5) | 10 (45.5) | |
| Present | 95 (62.1) | 58 (37.9) | |
| Resection margin | 0.816 | ||
| R0 | 85 (60.7) | 55 (39.3) | |
| R1 | 22 (62.9) | 13 (37.1) | |
| Median preoperative CA19-9, U/mL | 0.131 | ||
| <128 | 58 (66.7) | 29 (33.3) | |
| ≥128 | 49 (55.7) | 39 (44.3) | |
| Adequate adjuvant therapy | 0.516 | ||
| Yes | 43 (64.2) | 24 (35.8) | |
| No | 64 (59.3) | 44 (40.7) | |
Data are presented as number (%).
R0, no residual tumor; R1, microscopic residual tumor (corresponds to positive resection margins); CA19-9, carbohydrate antigen 19-9.