Table 1.
Optimized compound-dependent MS parameters for detection of the analytes and ISs.
| Compound | Precursor ion (m/z) | Product ion (m/z) | DP/V | CE/V | CXP/V |
|---|---|---|---|---|---|
| INH | 138.0 | 121.0 | 50.0 | 18.0 | 10.0 |
| RFP | 823.1 | 791.4 | 100.0 | 13.0 | 14.0 |
| EMB | 205.5 | 116.1 | 50.0 | 40.0 | 10.0 |
| PZA | 124.1 | 81.0 | 50.0 | 25.0 | 6.0 |
| INH-D4 | 142.0 | 125.1 | 50.0 | 21.0 | 10.0 |
| RFP-D8 | 831.5 | 799.6 | 92.0 | 15.0 | 15.0 |
| EMB-D4 | 209.3 | 120.1 | 50.0 | 21.0 | 10.0 |
| PZA-D3 | 127.2 | 84.1 | 60.0 | 24.0 | 6.0 |
PZA: pyrazinamide, INH: isoniazid, RFP: rifampicin, EMB: ethambutol, DP: declustering potential, CE: collision voltage, CXP: collision cell exit potential, IS: internal standard, and MS: mass spectrum.