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. 2020 Jul 8;2020:8365056. doi: 10.1155/2020/8365056

Figure 4.

Figure 4

DHP improved LSS-induced EC dysfunction. (a) NO, (b) ET-1, and (c) PGI2 levels after EA.hy 926 cells were exposed to LSS by a parallel flow chamber with DHP (0.1, 1, and 10 mg/L) treatment or not. The mRNA expression of (d) eNOS, (e) ET-1, and (f) PGIS by RT-qPCR (n = 3). (g) The fluorescence intensity of NO after EA.hy 926 cells were exposed to LSS by a parallel flow chamber. SD was depicted as vertical bars. ##p < 0.05, ###p < 0.001, compared with the control group (LSS, 0 min); ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, compared with the LSS group (LSS, 30 min). Significance was calculated by one-way ANOVA followed by unpaired t-test. n represents the independent experiments.