. 2019 Aug 22;22(Suppl 1):S-44–S-57. doi: 10.1089/jpm.2019.0130

Table 4.

Instruments and Outcomes for Each Specific Aim

SA1 (months 1–36)	All outcomes measured at approximately:	Patients	(1) Quality of life—Functional Assessment of Chronic Illness Therapy—Palliative Care (FACIT-Pal)^a65
	Five days after surgery		Subscales: (i) Functional Assessment of Cancer Therapy-General (FACT-G)
	One month after surgery		(ii) Trial Outcome Index (TOI)
	One month after surgery		(2) Demographics
	Three months after surgery		(3) Edmonton Symptom Assessment Score (ESAS)^b,69
	Three months after surgery		(4) Functional Assessment of Chronic Illness Therapy—Spiritual Well-being (FACIT-Sp-12)^b,68
	Six months after surgery
			(5) Mood symptoms including anxiety and depression subscales—PROMIS-29^66,67
			(6) Health care utilization^b (No. of postoperative hospitalizations and/or emergency room visits)
			(7) Presence of advance care planning^b
			(8) Prognostic understanding^b,70
			(9) Mortality^b
		Caregivers	(1) Demographics
			(2) Zarit Caregiver Burden Scale (ZBI-12)^b,71
			(3) Mood symptoms including anxiety and depression subscales—PROMIS-29^67,68
			(3) Functional Assessment of Chronic Illness Therapy—Spiritual Well-being (FACIT-Sp-12) family/companion measure^b,68
			(5) Prognostic understanding^b
SA2 (months 8–16)	In-depth interviews (approx., n = 20 in each arm)	Patients	Patient experiences and beliefs regarding management of symptoms, prognostic clarity, and advance care planning practices and beliefs
	In-depth interviews (approx., n = 20 in each arm)	Caregivers	Family member experiences and beliefs regarding prognostic clarity, caregiver experience, and patient experience of symptoms and advance care planning practices and beliefs
	In-depth interviews (approx., n = 8; all surgeons involved in the trial)	Surgeons	Surgeon experiences and beliefs regarding surgeon-alone vs. surgeon-palliative care team co-management of perioperative cancer patients and their families.
	In-depth interviews (approx., n = 10–15)	Palliative care clinicians	Palliative care team experiences and beliefs regarding surgeon-alone vs. surgeon-palliative care team co-management of perioperative cancer patients and their families.

^{^a}

Primary outcome.

^{^b}

Secondary outcome.