Table 2. Generic Over-the-Counter Sinus, Cold, and Allergy Drugs Marketed Under Multiple Brand Names in the United Statesa .
| Generic name | No. of different brand-name formulations | Selected brand names | |
|---|---|---|---|
| Single agent | Combination agents | ||
| Phenylephrine hydrochloride (oral) | 261 | Sudafed PE | Advil Congestion Relief, Alka-Seltzer Plus Cold & Cough Formula, Benadryl-D Allergy Plus Sinus, Children’s Dimetapp Cold and Allergy, Robitussin Cough & Cold, Sudafed PE Cold & Cough, Theraflu Cold & Cough, Tylenol Allergy Multi-Symptom |
| Dextromethorphan hydrobromide | 218 | Robitussin, Vicks DayQuil Cough & Congestion, Zicam Cough MAX | Alka-Seltzer Plus Cold & Cough Formula, Mucinex DM, Robitussin Cough Plus Chest DM, Sudafed PE Cold & Cough, Triaminic Cough & Sore Throat, Tylenol Cold & Cough Daytime |
| Pseudoephedrine hydrochloride | 130 | Sudafed | Advil Allergy Sinus, Aleve-D Sinus & Cold, Allegra-D, Clarinex-D, Claritin-D, Mucinex-D, Sudafed 12 Hour Pressure Plus Pain, Theraflu Max-D Severe Cold & Flu, Tylenol Sinus Severe Congestion Daytime, Zyrtec-D |
| Guaifenesin | 127 | Equate, Tussin, Mucinex, Robitussin | Cheratussin AC, Equate Tussin DM, Guaiatussin AC, Mucinex Fast-Max, Robafen DM Max, Robitussin Cough, ChestVicks, Zicam |
| Chlorpheniramine maleate | 86 | Chlor-Trimeton | Actifed Cold & Allergy, Alka-Seltzer Plus, Allerest Maximum Strength, Coricidin, Omnihist, Sinarest, Sudafed, Theraflu, Triaminic |
| Brompheniramine maleate | 42 | Ala-Hist, Dimetane | Bromfed, Children’s Dimetapp, LoHist |
| Diphenhydramine hydrochloride | 34 | Benadryl, Sominex, Unisom | Advil PM, Aleve PM, Bayer PM, Benadryl-D Allergy Plus Sinus, Excedrin PM, Goody’s PM, Midol PM, Motrin PM, Robitussin Night Time Cough & Cold, Sudafed PE Severe Cold, Theraflu Nighttime Severe Cold and Cough, Triaminic Night Time Cold & Cough, Tylenol Severe Allergy, Unisom With Pain Relief |
| Doxylamine succinate | 10 | Aldex, Unisom | Alka-Seltzer Plus, Coricidin, Tylenol Cold & Cough, Vicks NyQuil, Zicam Multisymptom Cold and Flu |
Data are from the US National Library of Medicine.6