Table 2.

Time-action of intermediate-acting and long-acting insulins (100 U/mL).

Insulin Type	Brand name	Onset of Action (hr)a	Peak Action (hr)	Duration of Action (hr)
Intermediate-acting U-100
NPH insulin	Humulin® N (40), Novolin® N (41)	1–2	2–8	14–24
Long-acting U-100
Insulin glargine	Lantus® (43), Basaglar®	NA	No pronounced peak	24
Insulin detemir	Levemir® (52)	NA	No pronounced peak	7.6–>24
Insulin degludec	Tresiba® (59)	NA	No pronounced peak	42

^a The onset of action is not relevant for long-acting insulins.