Table 4.

Concentrated insulins currently available in the United States.

Insulin Name	Concentration	Brand Name	Insulin Type	Notes
Bioequivalent to reference 100 U/mL				• Equivalent time-action profiles. • No dose adjustment needed.
Insulin lispro	200 U/mL	Humalog®	Prandial analog
Insulin degludec	200 U/mL	Tresiba®	Basal analog
Nonbioequivalent to reference 100 U/mL				• Different time-action profiles. • Dose adjustment needed for U-300. • No dose adjustment required for U-500R.
Insulin glargine	300 U/mL	Toujeo®	Basal analog
Human regular insulin	500 U/mL	Humulin® R U-500	Prandial/basal human