| 1 |
2013 |
pod of Lotus
corniculatus lectin |
d-galactose binding lectin |
human
leukemic cell line
(adherent type) (THP-1), lung cancer
cell line (HOP62), and colon cancer cell line (HCT116) |
48 |
THP-1, HOP62, and
HCT116 with IC50 of 39, 50, and 60 μg/mL, respectively. |
(26) |
| 2 |
2013 |
Bauhinia
ungulata L. seeds |
d-galactose (2.1 mM), lactose (0.96 mM), and N-acetyl-d-galactosamine (0.63 mM) |
human colon adenocarcinoma (HT-29 cell line) |
24 |
160 μg/mL |
(33,34) |
| 3 |
2014 |
Cicer arietinum seeds |
20 mM of N-acetyl-d-galactosamine |
human oral carcinoma
cells
(KB) |
48 |
37.5 μg/mL (IC50) |
(35) |
| 4 |
2014 |
soybean/seeds |
lactose specific |
HeLa (cervical cancer),
Hep2 (oral cancer), U373 MG (glioblastoma), HepG2 (liver cancer),
MDA MB 231 (breast cancer), and HaCaT (human keratinocyte cell line) |
72 |
HeLa, Hep2, HepG2, MDA MB
231, and U373 MG were 60.13 ± 3.5, 20.8 ± 1.2, 40.6 ± 6.1, 40.1 ± 7.7, and 51.0 ± 7.8 μg/mL, respectively |
(36) |
| 5 |
2016 |
Phaseolus
lunatus billb/seeds |
d-galactose, d-fructose, d-glucose, and mannitol |
HepG2, HeLa, and K562 |
48 |
13.7 μM (K562),
not reached to IC50 (HeLa and HepG2) |
(37) |
| 6 |
2016 |
lima bean variety (Phaseolus lunatus L. var. cascavel) |
only N-acetyl-d-galactosamine |
A375 melanoma cells |
48 and 72 |
100, 50, and 25 μg/mL at 48 h (73, 41, and 7%) at 72 h (83, 53,
and 0%) |
(38) |
| 7 |
2017 |
Calliandra
surinamensis leaf |
the monosaccharides glucose,
mannose, methyl-d glucopyranoside, N-acetylglucosamine, and galactose
or by the disaccharide maltose |
K562 (chronic myelogenous
leukemia) and T47D (breast cancer) |
72 |
IC50 observed
with the concentrations of 67.04 ± 5.78 and 58.75 ± 2.5 μg/mL |
(6) |
| 8 |
2017 |
Cratylia
mollis seed |
NIL |
human prostate adenocarcinoma (PC-3) |
24 |
the native as well as recombinant Cratylia mollis seed lectin; IC50 were
29.91 and 39.69 μg/mL, respectively |
(39) |
| 9 |
2018 |
soybean/seeds |
NIL |
B16F1 melanoma cells |
24 |
∼30%
cell growth
inhibition of B16 melanoma cells at a concentration of 35 μg/mL |
(40) |
| 10 |
2019 |
E. rheedii |
d-galactose (5 mM), cellobiose (5), and lactose (0.625 mM) |
lung cancer cells A549 and
human cervical cancer cells HeLa |
24 |
A549 and HeLa cells with
IC50 values 389 and 345 μg/mL, respectively |
NA |
