Table 1.
Phase | Time window | Clinical studies (number of participants)* | Physiological studies (number of participants) | Functional imaging studies (number of participants) |
---|---|---|---|---|
Preictal phase | 1 day before headache | Kelman (n = 897)a | Martins et al. (n = 22); Judit et al. (n = 14); Sand et al. (n = 11). | Schulte and May (n = 1)c |
Up to 2 days before headache | McKendrick et al. (n = 18) | Stankewitz et al. (n = 10); Luedtke et al. (n = 8)e | ||
Up to 3 days before headache | Giffin et al. (n = 97)b | Cao et al. (n = 40) | ||
>3 days before headache | Schwedt et al. (n = 112) | |||
Postictal phase | Within 1 day after headache | Kelman (n = 827)a; Blau (n = 40)a; Giffin et al. (n = 97)b | McKendrick et al. (n = 18) | Schulte and May (n = 1)c; Luedtke et al. (n = 8)e |
Within 2 days after headache | Martins et al. (n = 22)d | |||
>2 days after headache |
Several retrospective studies in the preictal phase are not listed due to small case numbers and high discrepancy.
Retrospective study.
Prospective electronic diary.
Longitudinal study, the patient measured 30 days in a row.
Postictal phase was defined as up to 48 hours after the ictal phase, but the data within 24 hours and 24–48 hours were not analyzed separately.
Longitudinal study, subjects measured 20–32 days consecutively.