Table 1.
Performance of the proposed joint model compared with the joint frailty model and shared frailty models ignoring Level-2 clustering
| N=300 | Proposed joint model (PJM) | Joint frailty model with Level-1 clustering only (JFM-L1) | Shared frailty model with Level-1 clustering only (SFM-L1) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Estimate | Bias | SE | SEM | CP | Estimate | Bias | SE | SEM | CP | Estimate | Bias | SE | SEM | CP |
| β= −0.5 | −0.483 | 3.4 | 0.215 | 0.190 | 0.944 | −0.491 | 1.8 | 0.239 | 0.221 | 0.947 | −0.327 | 52.9 | 0.153 | 0.152 | 0.787 |
| α= −0.5 | −0.502 | 0.4 | 0.262 | 0.284 | 0.958 | −0.521 | 4.2 | 0.285 | 0.287 | 0.943 | NA | ||||
| γ2= 0.5 | 0.506 | 1.2 | 0.181 | 0.178 | 0.986 | NA | NA | ||||||||
| γ1= 0.5 | 0.495 | 1.0 | 0.236 | 0.227 | 0.972 | 0.514 | 2.8 | 0.156 | 0.151 | 0.960 | NA | ||||
| θ2 =1.0 | 0.942 | 5.8 | 0.261 | 0.244 | 0.901 | NA | NA | ||||||||
| θ1= 1.0 | 1.005 | 0.5 | 0.105 | 0.099 | 0.944 | 1.356 | 35.6 | 0.195 | 0.110 | 0.227 | 0.665 | 50.4 | 0.207 | 0.105 | 0.234 |
| β= −0.5 | −0.487 | 2.6 | 0.201 | 0.190 | 0.963 | −0.501 | 0.2 | 0.221 | 0.221 | 0.950 | −0.346 | 44.5 | 0.152 | 0.159 | 0.819 |
| α= −0.5 | −0.521 | 4.2 | 0.296 | 0.269 | 0.936 | −0.473 | 5.4 | 0.297 | 0.288 | 0.940 | NA | ||||
| γ2= 1.0 | 1.060 | 6.0 | 0.242 | 0.207 | 0.938 | NA | NA | ||||||||
| γ1= 0.5 | 0.535 | 7.0 | 0.191 | 0.205 | 0.951 | 0.719 | 43.8 | 0.172 | 0.157 | 0.680 | NA | ||||
| θ2 =1.0 | 0.929 | 7.1 | 0.219 | 0.239 | 0.901 | NA | NA | ||||||||
| θ1= 1.0 | 0.989 | 1.1 | 0.089 | 0.099 | 0.988 | 1.348 | 34.8 | 0.187 | 0.113 | 0.223 | 0.673 | 48.6 | 0.230 | 0.117 | 0.305 |
| β= −0.5 | −0.505 | 1.0 | 0.209 | 0.200 | 0.952 | −0.511 | 2.2 | 0.229 | 0.231 | 0.967 | −0.307 | 62.9 | 0.167 | 0.163 | 0.768 |
| α= −0.5 | −0.480 | 4.0 | 0.282 | 0.251 | 0.912 | −0.399 | 20.2 | 0.305 | 0.291 | 0.917 | NA | ||||
| γ2= 2.0 | 2.032 | 1.6 | 0.367 | 0.372 | 0.959 | NA | NA | ||||||||
| γ1= 0.5 | 0.534 | 6.8 | 0.231 | 0.218 | 0.966 | 0.905 | 81.0 | 0.234 | 0.190 | 0.413 | NA | ||||
| θ2 =1.0 | 0.920 | 8.0 | 0.256 | 0.245 | 0.878 | NA | NA | ||||||||
| θ1= 1.0 | 0.985 | 1.5 | 0.114 | 0.110 | 0.932 | 1.349 | 34.9 | 0.194 | 0.129 | 0.270 | 0.556 | 79.9 | 0.180 | 0.146 | 0.176 |
NA: Not Applicable; Percent Relative Bias = mean of ; SE = Sampling standard error of the parameter estimate; SEM = Sampling mean of the standard error estimate (SEM); CP = Coverage probability of the corresponding 95% confidence interval