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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Apr 1;5(7):651–659. doi: 10.1016/j.bpsc.2020.03.008

Table 2.

Brain Tissue Relationships to EA-CSF at ages 1 and 2 years in typically developing.

Continuous Variables Year One (N=82) Year Two (N=49)
Mean (SD) R2 Est. p Mean (SD) R2 Est. p
EA-CSF (mm3) 78830.59 (13491.83) - - - 85285.73 (14635.93) - - -
CSF at Birth (mm3) 60213.59 (11805.56)a .309 0.584 <.001* 59236.32 (11233.64)b .107 0.431 0.048*
Intracranial (mm3) 938899.07 (90378.31) .211 0.069 <.001* 1061392.36 (108222.17) .260 0.069 <.001*
Gray Matter (mm3) 639499.57 (56240.98) .187 0.103 <.001* 731709.03 (74139.13) .270 0.103 <.001*
White Matter (mm3) 230625.04 (31376.44) .136 0.159 <.001* 258942.39 (28145.69) .217 0.242 <.001*
CSF (mm3) 68774.46 (10040.55) .311 0.750 <.001* 70740.95 (8483.61) .174 0.720 .002*
Total Ventricle (mm3) 6552.18 (3301.14) .039 0.807 .075 6830.35 (3878.06) .102 1.205 .025*
Average CT (mm) 2.84 (0.14)c .129 34039.4 .002* 2.68 (0.09)d .001 −4414.55 .850
Total SA (mm2) 141205.33 (12799.35)c .213 0.465 <.001* 167593.47 (14747.69)d .168 0.411 .004*
a

n=56

b

n=37

c

n=7

d

n=48.