Table 2.
Laboratory examination at admission
| All patients (N = 178) | Nonsevere (N = 129) | Severe (N = 49) | P value | |
|---|---|---|---|---|
| Blood cell counts | ||||
| White blood cells (3.5–9.5*109/L) | 5.95 (4.50–8.09) | 5.40 (4.40–7.05) | 7.90 (5.65–10.05) | 0.000 |
| Neutrophils (1.8–6.3*109/L) | 3.90 (2.66–5.64) | 3.51 (2.45–4.85) | 6.20 (3.88–8.51) | 0.000 |
| Lymphocytes (1.1–3.2*109/L) | 1.20 (0.82–1.61) | 1.29 (0.98–1.69) | 0.73 (0.45–1.22) | 0.000 |
| Monocytes (0.1–0.6*109/L) | 0.42 (0.30–0.60) | 0.42 (0.32–0.62) | 0.38 (0.27–0.55) | 0.547 |
| Eosinophils (0.02–0.52*109/L) | 0.08 (0.03–0.14) | 0.09 (0.05–0.14) | 0.03 (0.01–0.10) | 0.343 |
| Basophils (0–0.06*109/L) | 0.02 (0.01–0.03) | 0.02 (0.01–0.03) | 0.01 (0.00–0.02) | 0.004 |
| Hemoglobin (130–175 g/L) | 126.00 (115.00–133.25) | 126.00 (117.50–134.00) | 127.00 (111.50–132.50) | 0.114 |
| Platelets (125–350*109/L) | 236.00 (169.50–305.25) | 251.00 (202.00–317.00) | 186.00 (103.50– 249.00) | 0.000 |
| Coagulation function | ||||
| PT (9.2–15 s) | 13.17 (12.30–14.22) | 12.70 (12.15–13.59) | 14.55 (13.40–16.53) | 0.000 |
| INR (0.8–1.25) | 1.1 (1.03–1.19) | 1.06 (1.01–1.13) | 1.21 (1.13–1.36) | 0.000 |
| PT % (70–125) | 94.3% (89.53%–98.48%) | 96.4% (92.1%–99.3%) | 87.60% (80.10%–92.15%) | 0.000 |
| APTT (21–37 s) | 27.54 (25.31–30.18) | 25.99 (25.11–29.33) | 29.25 (26.95–32.84) | 0.057 |
| FIB (2–4 g/L) | 3.26 (2.79–3.99) | 3.23 (2.80–3.70) | 3.62 (2.70–4.33) | 0.780 |
| TT (10–20 s) | 15.91 (14.94–15.83) | 15.68 (14.79–16.69) | 16.35 (15.69–17.47) | 0.011 |
| D-Dimer (0–0.55 mg/L) | 0.56 (0.33–1.12) | 0.42 (0.28–0.79) | 1.05 (0.68–5.90) | 0.000 |
| Blood biochemistry | ||||
| ALT (9–50 IU/L) | 29.85 (16.60–52.63) | 28.80 (15.75–50.15) | 30.80 (19.00–58.30) | 0.487 |
| AST (9–60 IU/L) | 23.90 (17.20–36.60) | 22.6 (16.7–32.03) | 27.80 (19.30–40.55) | 0.102 |
| TP (68–85 g/L) | 62.60 (57.50–67.30) | 63.95 (67.95– 58.85) | 57.80 (52.80–63.15) | 0.000 |
| ALB (40–50 g/L) | 34.50 (30.30–38.00) | 36.00 (32.88–39.10) | 30.90 (27.60–33.65) | 0.000 |
| GLB (20–35 g/L) | 34.50 (30.30–38.00) | 26.70 (25.20–29.60) | 26.50 (23.90–31.40) | 0.576 |
| Blood glucose (3.9–6.11 mmol/L) | 5.22 (4.64–6.55) | 5.06 (4.61–5.84) | 6.15 (5.08–9.16) | 0.002 |
| B–type natriuretic peptide (0–100 pg/mL) | 11.05 (0.01–48.24) | 0.01 (0.01–33.74) | 40.55 (2.52–116.64) | 0.052 |
| Serum creatinine (57–97 μmol/L) | 66.70 (56.83–78.85) | 67.35 (57.88–77.75) | 65.35 (55.78–79.45) | 0.402 |
| LDH(120–250 IU/L) | 196.10 (164.80–278.70) | 188.25 (162.13–219.33) | 302.70 (198.90–479.00) | 0.000 |
| Myoglobin (0–65 ng/mL) | 7.58 (3.36–21.46) | 5.13 (2.92–11.97) | 25.14 (9.05–30.22) | 0.022 |
| Troponin (0–0.04 ng/mL) | 0.01 (0.01–0.01) | 0.01 (0.01–0.01) | 0.01 (0.01–0.05) | 0.125 |
| Infection related parameters | ||||
| PCT (0–0.05 ng/mL) | 0.05 (0.03–0.12) | 0.03 (0.03–0.07) | 0.13 (0.07–0.21) | 0.564 |
| CRP (0–4 mg/L) | 7.25 (1.59–60.74) | 4.22 (0.96–15.75) | 64.74 (6.58–119.03) | 0.000 |
Data are median value (interquartile range)
PT prothrombin time, INR international normalized ratio, APTT activated partial thromboplastin time, FIB fibrinogen, TT thrombin time, LDH lactate dehydrogenase, ALT alanine aminotransferase, AST aspartate aminotransferase, TP total protein, ALB albumin, GLB globulin, PCT procalcitonin, CRP C-reactive protein