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. 2020 Jun 5;14(4):544–555. doi: 10.1007/s12072-020-10056-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Representative mass spectra in ESI–MS analysis in the range of m/z 450–960 scanning mode for the detection of phospholipid species. a PL spectra represent lipid extract from one of ten aliquot quality control (QC); b PL spectra represent lipid extract from one of benign hepatic tissue (BHT) samples and c PL spectra represent lipid extract from one of hepatocellular carcinoma (HCC) samples; d correlation and regression analyses of mean concentrations in 13 PL classes between two quantitative methods. The plot showed a significantly linear correlation between mean concentrations of 13 PL classes in nmol/mg wet weight tissue (wwt) and that in nmol/mg protein (r² = 0.9999, p < 0.0001)