Fig. 3. Seven hallmark gene pathways are enriched for ageing-related genes.
N number of genes of interest vs. total number of genes in the gene set for which eQTL are available. P Nominal P value of the hypergeometric test for enrichment (against 24,670 background genes). Pbonf Bonferroni-corrected P value for testing seven hallmark pathways (containing at least three genes). The figure shows individual genes on the x-axis and hallmark pathways are listed on the y-axis, matching the order of the table. Squares represent the presence of a gene in the gene set.