Table 2.
Baseline characteristics of HCV/C. sinensis co-infection group and HCV or C. sinensis mono-infection groups.
| Hepatitis B (n = 46) | HBV/C. sinensis coinfection (n = 46) | C. sinensis (n = 46) | P1 | P2 | |
|---|---|---|---|---|---|
| Age (years, mean ± SD) | 50.59 ± 10.01 | 50.65 ± 9.81 | 50.63 ± 9.76 | 0.999 | 0.999 |
| Sex (Male, %) | 31 (67.4) | 31 (67.4) | 31 (67.4) | 1.000 | 1.000 |
| ALT (IU/mL) | 41.0 (34.3, 49.5) | 38.5 (32.8, 51.0) | 39.5 (30.5, 49.3) | 0.56 | 0.912 |
| AST (IU/mL) | 33.0 (26.0, 42.5) | 32.5 (27.8, 39.0) | 29.5 (25.0, 40.3) | 0.922 | 0.137 |
| Total protein (g/L) | 78.0 (72.8, 84.3) | 77.0 (72.0, 83.3) | 78.5 (72.0, 81.3) | 0.46 | 0.587 |
| ALB (g/L) | 44.5 (41.0, 48.3) | 44.0 (41.0, 47.0) | 44.5 (42.0, 46.0) | 0.45 | 0.543 |
| ALB/GLB | 1.40 (1.08, 1.52) | 1.36 (1.19, 1.54) | 1.34 (1.17, 1.59) | 0.934 | 0.936 |
| TBIL (µmol/L) | 18.0 (13.0, 23.0) | 18.0 (14.0, 22.0) | 17.0 (13.8, 21.0) | 0.745 | 0.766 |
| IBIL (µmol/L) | 11.0 (6.75, 16.0) | 9.0 (7.0, 14.0) | 10.0 (6.0, 13.0) | 0.484 | 0.829 |
| GGT (U/L) | 28.5 (18.8, 59.5) | 31.5 (21.8, 74.3) | 33.5 (24.8, 65.8) | 0.292 | 0.614 |
| ALP (U/L) | 69.0 (50.0, 83.0) | 61.5 (45.5, 72.3) | 67.0 (53.8, 79.5) | 0.184 | 0.183 |
| Creatinine (μmol/L) | 62.0 (54.5, 73.0) | 64.5 (58.0, 70.5) | 63.5 (55.5, 75.3) | 0.763 | 0.699 |
| BUN (mmol/L) | 5.1 (4.4, 5.9) | 5.25 (4.50, 6.03) | 5.5 (4.6, 6.2) | 0.716 | 0.39 |
| Uric acid (µmol/L) | 354 (304, 435) | 362.0 (308.3, 422.8) | 360.0 (311.5, 435.3) | 0.679 | 0.885 |
| TG (mmol/L) | 1.34 (0.95, 1.83) | 1.52 (1.11, 2.20) | 1.79 (1.19, 2.91) | 0.226 | 0.328 |
| Cholesterol (mmol/L) | 3.45 (2.80, 3.88) | 3.60 (3.10, 4.30) | 3.90 (3.30, 4.50) | 0.088 | 0.148 |
| LDL (mmol/L) | 1.23 (0.91, 1.56) | 1.40 (0.88, 2.02) | 1.45 (1.12, 2.08) | 0.517 | 0.293 |
| GLU (mmol/L) | 3.40 (3.10, 3.55) | 3.80 (3.30, 4.90) | 3.50 (3.25, 4.15) | 0.388 | 0.873 |
| WBC (*109/L) | 6.96 (6.22, 8.27) | 6.78 (5.75, 7.90) | 6.73 (5.81, 7.63) | 0.571 | 0.932 |
| RBC (*1,012/L) | 4.64 (4.23, 5.15) | 4.64 (4.16, 5.00) | 4.67 (4.40, 4.97) | 0.363 | 0.679 |
| PLT (*109/L) | 159.5 (133.8, 190.0) | 161.0 (129.8, 198.0) | 178.5 (145.8, 216.5) | 0.767 | 0.135 |
| Lymphocyte (*109/L) | 2.27 (1.89, 3.04) | 2.41 (1.95, 3.04) | 2.38 (1.96, 2.71) | 0.87 | 0.582 |
| Neutrophil (*109/L) | 3.75 (3.27, 4.22) | 3.51 (2.80, 4.30) | 3.29 (2.90, 4.26) | 0.461 | 0.746 |
| Eosinophil count (*109/L) | 0.15 (0.11, 0.21) | 0.18 (0.12, 0.34) | 0.19 (0.12, 0.42) | 0.509 | 0.673 |
| Haemoglobin (g/L) | 153.5 (139.0, 169.3) | 155.5 (134.5, 167.0) | 152.5 (144, 160) | 0.54 | 0.749 |
| lg10 (HBV-DNA) | 3.39 (2.30, 4.63) | 2.91 (2.36, 5.60) | – | 1 | – |
| APRI | 0.45 (0.31, 0.62) | 0.47 (0.33, 0.65) | 0.38 (0.28, 0.47) | 0.904 | 0.049 |
| FIB-4 | 1.70 (1.12, 2.44) | 1.65 (1.08, 2.69) | 1.28 (1.02, 1.80) | 0.907 | 0.082 |
ALT alanine aminotransferase, AST aspartate aminotransferase, ALB albumin, GLB globulin, ALB/GLB albumin to globulin, TBIL total bilirubin, IBIL indirect bilirubin, GGT gamma-glutamyl transpeptidase, ALP alkaline phosphatase, BUN blood urea nitrogen, TG triglyceride, LDL low-density lipoprotein, GLU glucose, WBC white blood cell, RBC red blood cell, PLT platelet, APRI, levels and AST to PLT ratio index, FIB-4 fibrosis-4 scores.