Table 3.
Baseline characteristics of HBV/C. sinensis co-infection group and HBV or C. sinensis mono-infection groups.
| Hepatitis C (n = 59) | HCV/C. sinensis coinfection (n = 59) | C. sinensis (n = 59) | P1 | P2 | |
|---|---|---|---|---|---|
| Age (years, mean ± SD) | 57.78 ± 7.91 | 57.54 ± 8.47 | 57.46 ± 8.33 | 0.876 | 0.956 |
| Sex (Male, %) | 46 (78.0) | 46 (78.0) | 46 (78.0) | 1.000 | 1.000 |
| ALT (IU/mL) | 54.0 (41.0, 81.0) | 62.0 (42.0, 103.0) | 38.0 (31.0, 48.0) | 0.236 | < 0.001 |
| AST (IU/mL) | 45.0 (32.0, 67.0) | 54.0 (38.0, 87.0) | 28.0 (24.0, 35.0) | 0.052 | < 0.001 |
| Total protein (g/L) | 78.0 (72.0, 85.0) | 79.0 (75.0, 85.0) | 77.0 (72.0, 82.0) | 0.292 | 0.031 |
| ALB (g/L) | 43.0 (41.0, 45.0) | 43.0 (42.0, 45.0) | 44.0 (42.0, 46.0) | 0.184 | 0.539 |
| ALB/GLB | 1.22 (1.07, 1.43) | 1.18 (1.09, 1.35) | 1.36 (1.23, 1.53) | 0.51 | 0.001 |
| TBIL (µmol/L) | 17.0 (12.0, 22.0) | 19.0 (14.0, 24.0) | 16.0 (13.0, 20.0) | 0.164 | 0.036 |
| IBIL (µmol/L) | 10.0 (6.0, 13.0) | 11.0 (7.0, 15.0) | 9.0 (6.0, 12.0) | 0.111 | 0.025 |
| GGT (U/L) | 53.0 (29.0, 104.0) | 69.0 (37.0, 143.0) | 36.0 (25.0, 69.0) | 0.114 | 0.001 |
| ALP (U/L) | 73.0 (61.0, 93.0) | 78.0 (61.0, 93.0) | 70.0 (56.0, 81.0) | 0.577 | 0.035 |
| Creatinine (μmol/L) | 65.0 (58.0, 73.0) | 65.0 (56.0, 75.0) | 66.0 (58.0, 74.0) | 0.732 | 0.724 |
| BUN (mmol/L) | 5.5 (4.5, 6.6) | 5.80 (4.60, 6.60) | 5.5 (4.8, 6.2) | 0.628 | 0.554 |
| Uric acid (µmol/L) | 363.0 (330.0, 404.0) | 377.0 (315.0, 424.0) | 365.0 (305.0, 438.0) | 0.317 | 0.844 |
| TG (mmol/L) | 1.38 (0.85, 1.73) | 1.28 (0.89, 2.04) | 1.54 (1.19, 2.54) | 0.861 | 0.020 |
| Cholesterol (mmol/L) | 3.30 (2.80, 3.70) | 3.30 (2.90, 4.00) | 3.80 (3.20, 4.40) | 0.425 | 0.003 |
| LDL (mmol/L) | 1.22 (0.91, 1.68) | 1.27 (0.87, 1.77) | 1.66 (1.16, 2.23) | 0.998 | 0.011 |
| GLU (mmol/L) | 3.85 (3.53, 4.05) | 4.10 (3.60, 4.40) | 3.70 (3.35, 6.48) | 0.377 | 0.535 |
| WBC (*109/L) | 6.28 (4.82, 7.73) | 6.02 (5.12, 7.30) | 6.81 (5.83, 8.09) | 0.72 | 0.012 |
| RBC (*1,012/L) | 4.49 (4.28, 4.97) | 4.57 (4.18, 4.93) | 4.64 (4.34, 4.85) | 0.901 | 0.825 |
| PLT (*109/L) | 144.0 (102.0, 179.0) | 136.0 (106.0, 176.0) | 180.0 (147.0, 215.0) | 0.677 | < 0.001 |
| Lymphocyte (*109/L) | 2.12 (1.73, 2.68) | 2.00 (1.73, 2.49) | 2.30 (1.97, 2.53) | 0.62 | 0.029 |
| Neutrophil (*109/L) | 3.28 (2.29, 4.66) | 3.30 (2.63, 4.03) | 3.62 (2.88, 4.40) | 0.733 | 0.039 |
| Eosinophil count (*109/L) | 0.15 (0.09, 0.20) | 0.17 (0.11, 0.28) | 0.25 (0.16, 0.47) | 0.177 | 0.004 |
| Haemoglobin (g/L) | 152.0 (144.0, 161.0) | 153.0 (142.0, 164.0) | 153.0 (145.0, 161.0) | 0.784 | 0.981 |
| lg (HCV-RNA) | 6.43 (5.71, 6.92) | 6.27 (5.49, 6.82) | – | 0.587 | – |
| HCV-Genotype (1b, %) | 32 (54.2) | 27 (45.8) | – | 0.361 | – |
| APRI | 0.74 (0.49, 1.47) | 0.88 (0.55, 1.88) | 0.35 (0.28, 0.52) | 0.156 | < 0.001 |
| FIB-4 | 2.54 (1.65, 4.22) | 3.01 (1.93, 5.39) | 1.52 (1.18, 2.08) | 0.188 | < 0.001 |
ALT alanine aminotransferase, AST aspartate aminotransferase, ALB albumin, GLB globulin, ALB/GLB albumin to globulin, TBIL total bilirubin, IBIL indirect bilirubin, GGT gamma-glutamyl transpeptidase, ALP alkaline phosphatase, BUN blood urea nitrogen, TG triglyceride, LDL low-density lipoprotein, GLU glucose, WBC white blood cell, RBC red blood cell, PLT platelet, APRI, levels and AST to PLT ratio index, FIB-4 fibrosis-4 scores.