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. 2020 Jul 16;10:11795. doi: 10.1038/s41598-020-68625-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Multimodal imaging of the right eye of a 30-year old woman with Sickle cell retinopathy (SS), stage 3. (A) Red/green ultra-wide field retinography with neovascular lesions (white arrows). (B) The ultra-wide field fluorescein angiography shows temporal peripheral non-perfusion area (white stars), and preretinal neovascular lesions (white arrows). (C) OCT angiography shows microvascular abnormalities in the perifoveal area in the superficial capillary plexus: areas of rarefied capillary (yellow arrow), and disruption of the perifoveal anastomotic capillary arcade (white arrow-head). (D) B-scan with the limits in orange of the SCP segmentation. Blood flow appears in red. (E) OCT angiography shows microvascular abnormalities in the perifoveal area in the deep capillary plexus: enlargement non-perfusion area (dotted arrow). (F) B-scan with the limits in green of the DCP segmentation. Blood flow appears in red.