Table 2.
Summary of demographic and clinical characteristics of HIV-infected participants stratified by pulmonary disease status.
| Characteristic | Statistic | Normotensive | Pulmonary hypertensive | Total |
|---|---|---|---|---|
| Gender | ||||
| Male | n (%) | 19 (59%) | 13 (41%) | 32 (82%) |
| Female | n (%) | 4 (57%) | 3 (43%) | 7 (17%) |
| Ethnicity | ||||
| African-American | n (%) | 8 (38%) | 6 (37%) | 14 (37%) |
| Caucasian | n (%) | 9 (42%) | 10 (62%) | 19 (51%) |
| Other | n (%) | 4 (19%) | – | 4 (10%) |
| CD4 counts | ||||
| Asymptomatic | n (%) | 21 2(91%) | 12 (75%) | 33 (84%) |
| AIDS | n (%) | 2 (8%) | 4 (25%) | 6 (15%) |
| Antiretroviral therapy | ||||
| Naïve | n (%) | 5 (21%) | 2 (12%) | 7 (17%) |
| Experienced | n (%) | 18 (78%) | 14 (87%) | 32 (82%) |
| HIV viral loads | ||||
| Viremic | n (%) | 13 (56%) | 9 (56%) | 22 (56%) |
| Suppressed | n (%) | 10 (43%) | 7 (43%) | 17 (43%) |
| Hemodynamics | ||||
| mean PAP (by RHC) | Mean ± SD | 18.20 ± 2.8 | 36.06 ± 11.9 | |
| Mean PASP (by echo) | Mean ± SD | 33.57 ± 6.4 | 51.19 ± 23.5 | |
We grouped the research subjects enrolled into this study as per the following criteria: pulmonary normotensive (mPAP < 25 mm Hg by RHC or PASP by echocardiography if RHC was not performed), pulmonary hypertensive (mPAP > 25 mm Hg by RHC or PASP by echocardiography if RHC was not performed); asymptomatic for HIV disease (CD4 counts > 200 cells/ul); AIDS (CD4 counts < 200 cells/ul); antiretroviral treatment naïve if they reported having no experience with antiretroviral therapy any time on or before enrollment into this study; viremic if patient had HIV viral loads > 40 copies/ml at sampling time or 6 months before and; suppressed if patient had HIV viral loads < 40 copies/ml at sampling time or 6 months before.