Table 2.
Clinical characteristics of LHI patients with and without brain herniation
| Brain herniation, N (%) | |||
|---|---|---|---|
| No (N = 46) | Yes (N = 38) | P value | |
| Age (y), mean ± SD | 65.3 ± 13.7 | 57.6 ± 13.6 | 0.012* |
| Sex (Male/Female) | 31/15 | 27/11 | 0.718 |
| Mean Arterial Pressure(mmHg), mean ± SD | 105.0 ± 15.6 | 101.6 ± 14.1 | 0.294 |
| NIHSS, mean ± SD | 18.4 ± 6.0 | 18.9 ± 6.6 | 0.706 |
| GCS, median/IQR | 9 (8‐11) | 7 (5‐9) | <0.01** |
| Temperature (℃),median/IQR | 36.9 (36.5‐37.3) | 36.7 (36.4‐37.3) | 0.454 |
| Hypertension | 21 (45.7%) | 14 (36.8%) | 0.415 |
| Diabetes | 8 (17.4%) | 9 (23.7%) | 0.475 |
| Hyperlipidemia | 7 (15.2%) | 2 (5.3%) | 0.142 |
| Stroke history | 11 (23.9%) | 4 (10.5%) | 0.111 |
| Coronary heart disease | 4 (8.7%) | 5 (13.2%) | 0.51 |
| Atrial fibrillation | 16 (34.8%) | 13 (34.2%) | 0.956 |
| Heart failure | 12 (26.1%) | 5 (13.2%) | 0.142 |
| Smoking | 20 (43.5%) | 23 (60.5%) | 0.12 |
| Drinking alcohol | 18 (39.1%) | 19 (50.0%) | 0.318 |
| Family history of stroke | 8 (17.4%) | 7 (18.4%) | 0.902 |
| TOAST classification | |||
| Large artery atherosclerosis | 28 (60.9%) | 22 (57.9%) | |
| Cardiac embolism | 16 (34.8%) | 14 (36.8%) | |
| Others | 2 (4.3%) | 2 (5.3%) | 0.955 |
| Postinfarct hemorrhage | 6 (13.0%) | 2 (5.3%) | 0.227 |
| Infarction volume on D2 (cm3), mean ± SD | 122.9 ± 79.2 | 227.6 ± 98.2 | <0.01** |
| Edema volume on D2 (cm3), median (IQR) | 31.0 (19.9‐54.3) | 94.2 (38.8‐115.7) | <0.01** |
| Intravenous thrombolysis | 4 (8.7%) | 9 (23.7%) | 0.059 |
| Intravascular treatment | 4 (8.7%) | 1 (2.6%) | 0.242 |
| Mechanical ventilation | 18 (39.1%) | 28 (73.7%) | <0.01** |
| Decompressive craniectomy | 6 (13.0%) | 23 (60.5%) | <0.01** |
| mRS at 6 month (median/IQR) | 5 (3‐5) | 6 (5‐6) | <0.01** |
The continuous data were described as mean ± SD for normally distributed data and as median/IQR for non‐normally distributed data. Categorical data were shown as N (%). The P values were obtained from Student's t‐test, Mann‐Whitney U‐test or chi‐square test, when appropriate.
*
P < .05, ** P < .01.