Table 2:
Anova F-test with the corresponding p-values for distributions of synonymous mutation scores (SMS) computed from observed and non-observed mutations in S ORF and N ORF and for different models of synonymous mutations (uniform bias, transition versus transversion bias (trt-trv), virus codon bias, with, and without CpG force). In the uniform case, we did not specify the p-value since all mutations have the same SMS.
| F-test (S ORF) | F-test (N ORF) | p-value (S ORF) | p-value (N ORF) | |
|---|---|---|---|---|
| Uniform bias | 1 | 1 | - | - |
| Uniform bias + CpG force | 79 | 240 | 1 · 10−18 | 5 · 10−50 |
| trt-trv bias | 0.6 | 5 · 10−6 | > 0.05 | > 0.05 |
| trt-trv bias + CpG force | 53 | 159 | 4 · 10−13 | 1 · 10−34 |
| Virus codon bias | 411 | 42 | < 10−50 | 1 · 10−10 |
| Virus codon bias + CpG force | 408 | 107 | < 10−50 | 3 · 10−24 |