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[Preprint]. 2020 Feb 25:3541361. [Version 1] doi: 10.2139/ssrn.3541361

Table 1.

IEDB inventory of coronavirus B and T cell epitopes

A)

Coronavirus
Alpha Beta
Gamma
Epitope set Type SARS-CoV MERS-CoV Other Total
B cell Conformational 18 27 23 2 11 81
Linear 81 405 5 60 30 581

T cell 61 164 25 54 16 320
B)

Coronavirusb
Alpha Beta
Gamma
Epitope set Host SARS-CoV MERS-CoV Other Total

B cella Humans 0 306 16 0 0 322
Mice 62 154 9 58 20 303
Other 42 142 5 6 23 218
Tg mice 0 0 0 0 0 0

T cell Humans 2 92 0 1 0 95
Mice 16 99 25 53 1 194
Other 46 1 0 0 15 62
Tg mice 0 29 0 0 0 29
C)

SARS protein Bcell T cell

Spike glycoprotein 279 48
Nucleoprotein 113 33
Membrane protein 20 4
Replicase polyprotein lab 8 9
Protein 3a 2 7
Envelope small membrane protein 2 0
Non-structural protein 3b 2 0
Protein 7a 2 0
Protein 9b 2 0
Non-structural protein 6 1 0
Protein non-structural 8a 1 0
a.

B cell includes both conformational and linear epitipes.

b.

Totals between A) and B) may not be equal as several epitopes are recognized in multiple species.

a.

T cell epitope total includes epitopes recognized in humans and/or transgenic mice.