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. 2020 Jul 17;5:120. doi: 10.1038/s41392-020-0173-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Characteristics and cellular uptake of tFNAs. a Structure of tFNAs. b Results of HPCE showing the successful assembly of tFNAs. c A TEM image showing the tFNA morphology. d Size of the tFNA molecule. e Zeta potential of the synthesized tFNAs. f Cy5-ssDNAs and Cy5-tFNAs taken up by HaCaT cells (Cy5-ssDNAs and Cy5-tFNAs: red; nucleus: blue; cytoskeleton:green). Scale bars are 100 pm. g Cy5-ssDNAs and Cy5-tFNAs taken up by HSF cells (Cy5-ssDNAs and Cy5-tFNAs: red; nucleus: blue; cytoskeleton:green). Scale bars are 100 pm