Figure 1. Diffusion tensor magnetic resonance imaging of brain in preschoolers, showing associations between use of 
screen-based media and white-matter integrity. White-matter voxels exhibit a statistically significant correlation between ScreenQ scores (which indicate screen-based media use, ie, how intensive digital media have been used) and lower fractional anisotropy (FA; A), as well as higher radial diffusivity (RD; B); both indicate fiber tract in the analysis of whole-brain images. All data were controlled for household income level and child age (P > 0.05, familywise error–corrected). The color code 
depicts the magnitude or slope of correlation (change in the diffusion tensor imaging parameter for every point increase in ScreenQ score). Adapted from ref 24: Hutton JS, Dudley J, Horowitz-Kraus T, DeWitt T, Holland SK. Associations between screen-based media use and brain white matter integrity in preschool-aged children. JAMA Pediatr. 2019;e193869. 
doi:10.1001/jamapediatrics.2019.3869. Copyright © American Medical Association 2019.