Table 3.

The potential of Soshihotang as a treatment option for COVID-19.

Effects of Soshihotang	Contents	Expected effects in COVID-19
Anti-SARS-CoV-2 activity57	Components of soshihotang show Anti-SARS-CoV-2 activity (baicalein, beta-carotene, coptisine, formononetin, glycyrrhizic acid, kaempferol, moupinamide, quercetin, saikosaponin A, saikosaponin B2, saikosaponin D, and 7-methoxy-2-methyl isoflavone)	Inhibition of SARS-CoV-2 activity
Immunomodulatory effect58	Soshihotang increases lymphocytes only in the immunosuppressive model (invalid in the normal animal model)	Correction of early lymphocyte degradation in patients with COVID-19
Hepato-protective effects15, 16, 17, 18, 19, 20, 21, 25	Soshihotang has been utilized in patients with HBV or HCV infection and has shown significant antiviral and hepato-protective effects	Management of liver injury in patients with COVID-19

COVID-19; coronavirus disease 2019.

HBV; Hepatitis B virus.

HCV; Hepatitis C virus.