Table 2.

Unadjusted comparisons of outcomes between patients with and without moderate pre-stroke disability.

	mRS 0–1	mRS 2–3	Odds ratio* [95% CI]	P-value	Adjusted Odds Ratio| | [95%CI]
Primary Outcome
mRS 0–1 or No disability accumulated, n/total (%)	172/469 (36.7)	65/243 (26.7)	0.63 [0.45–0.88]	0.008	0.90 [0.60–1.35]
Secondary Outcomes
No disability accumulated, n/total (%)	105/469 (22.4)	65/243 (26.7)	1.27 [0.88–1.81]	0.20	1.90 [1.24–2.94]
Change in UW-mRS, mean±SD / total	−0.35±0.35 / 469	−0.38±0.32 / 243	−0.04 [−0.09–0.02]†	0.17‡
Death, n/total (%)	67/469 (14.3)	98/243 (40.3)	4.06 [2.82–5.86]	<0.001	2.95 [1.84–4.78]
Length of hospital stay, days, median [IQR] / total	5 [3–8] / 502	5 [3–9] / 259	0.90 [−0.07–1.86]†	0.06§
Procedural Outcomes
Symptomatic ICH, n/total (%)	36/496 (7.3)	16/259 (6.2)	0.84 [0.45–1.52]	0.56
mTICI 2b-3, n/total (%)	435/502 (86.7)	217/259 (83.8)	0.80 [0.53–1.22]	0.28

^*Ratio of odds in mRS 2–3 to odds in mRS 0–1 group with corresponding p-value of a Fisher’s exact test are provided.

^†Numerical change in the outcome from mRS 0–1 to mRS 2–3 modeled by unadjusted linear regression.

^‡T-test and

^§Mann-Whitney U test.

^{| |}Adjusted for age, sex, initial glucose, NIHSS on presentation, time to recanalization, intravenous thrombolysis, ASPECT score, and successful recanalization