Table I:
Drug Dynamics Variables
| Variables | Unit | Description |
|---|---|---|
| TDM1 | nM | Free T-DM1 |
| HER2 | nM | Free HER2 |
| HER2e | nM | HER2 in endosome |
| B | nM | T-DM1 bound to HER2 |
| Be | nM | T-DM1 bound to HER2 in endosome |
| DM1 | nM | DM1 |
| Tras | nM | Trastuzumab |
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